Proton Beam Therapy vs. Traditional Radiation

For men with prostate cancer, the side effects of conventional radiation treatment (including CyberKnife/SBRT) can have important quality of life implications—especially relating to urinary, gastrointestinal, and erectile function—as the organs controlling these functions also receive a lot of unnecessary radiation. Alternatively, proton therapy delivers considerably less radiation to healthy organs and tissues resulting in less frequent and/or less severe side effects, and often no side effects at all.

Proton therapy is particularly beneficial for men with high-risk prostate cancer that has spread or is at risk of spreading to the lymph nodes. Compared to conventional treatment, proton therapy can deliver high radiation doses to the lymph nodes while better sparing the healthy bowel and bladder.

Additionally, prostate tumors treated with proton therapy reduce the risks of secondary cancers in the treated areas. Proton therapy is also effective in treating patients with prostate cancer that has returned after previous radiation therapy or prostatectomy.

Proton therapy is outpatient, noninvasive and totally painless. The majority of patients continue on as normal, without having their quality of life throughout treatment impacted by their proton therapy.

Entire Treatment in 5 Sessions

For eligible patients, 5-Treatment Stereotactic Body Radiation Therapy (SBRT) Proton Therapy is an option for both new and recurrent prostate cancer. Traditionally, radiation therapy for prostate cancer has been administered daily over five to eight weeks but with 5-treatment SBRT, the treatment takes place in just one to two weeks. This shorter treatment course of higher doses of radiation is possible due to proton particles being more controllable and highly targeted than the photon particles used in other forms of radiation therapy.

Fewer Side Effects

Proton therapy kills prostate cancer cells with a very high radiation dose. But because the protons are also highly targeted and are customized to travel to a specified depth in the body and then stop, they deliver more radiation to the prostate cancer and less to healthy organs surrounding the prostate gland, like the rectum, bowel, and bladder. As a result, proton therapy can better preserve your quality of life and minimizes the likelihood of side effects including:

  • Radiation cystitis (urinary incontinence, blood in urine)
  • Radiation proctitis (rectal pain, blood in stool)
  • Erectile dysfunction
  • Fatigue
  • Skin irritation

To further help lessen side effects and protect the rectum from unnecessary radiation, a hyaluronic acid-based gel spacer may be inserted between the prostate and the rectum prior to the start of treatment.

Types of Prostate Cancer Treated at the New York Proton Center

The New York Proton Center treats the following prostate cancers with proton beam therapy.

Localized prostate cancer includes stage 1, stage 2, and stage 3 cancer that has not grown into nearby tissues or more distant body parts. There are three types:

Very-low-risk and low-risk prostate cancer, each of which are unlikely to grow or spread for a long time, if at all.
Intermediate-risk prostate cancer, which may grow or spread in a few years.
High-risk prostate, which has the highest likelihood of spreading and, even after treatment, recurring.

Prostate cancer will sometimes grow quickly and spread to lymph nodes, pea-sized pieces of tissue that filter a waste product called lymph. When this happens, a larger area needs to be targeted for treatment that includes the prostate gland and the lymph nodes. Proton therapy is particularly beneficial when treating large areas in the pelvis.

Data suggest that men who have undergone prostatectomy for prostate cancer may benefit from follow-up treatment with proton therapy, depending on several factors:

Gleason score
Seminal vesicle and lymph nodes involvement
PSA levels

Among men treated for prostate cancer, up to 30 percent see their cancer return. Fewer than half of them can be cured by traditional treatment.

Proton therapy can treat these “recurrent” tumors more safely than other methods, giving patients a better chance for a cure.

Prostate Cancer Proton Therapy FAQs

Read our frequently asked questions about proton therapy for prostate cancer.

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