Proton therapy for prostate cancer

For men with prostate cancer, the side effects of conventional radiation treatment can have serious quality of life implications—particularly relating to urinary, bowel and erectile function.

 

Proton therapy kills prostate cancer cells with a very high radiation dose. But because the protons are also highly targeted, they deliver more radiation to the prostate cancer and less to healthy organs surrounding the prostate gland, like the rectum, bowels and bladder. As a result, proton therapy minimizes the likelihood of side effects.

 

Proton therapy vs. traditional radiation

Proton therapy is particularly beneficial for men with high-risk prostate cancer that has spread to the lymph nodes. Compared to conventional treatment, proton therapy can deliver high radiation doses to the lymph nodes while better sparing the healthy bowel and bladder.

 

Additionally, prostate tumors treated with proton therapy reduce the risks of secondary cancers in the treated areas. Proton therapy is also highly effective in treating patients with prostate cancer that has returned after previous radiation therapy or prostatectomy.

 

Proton therapy is outpatient, noninvasive and totally painless. The majority of patients continue on as normal, without having their quality of life throughout treatment impacted by their proton therapy.

Types of prostate cancer treated at the New York Proton Center

The New York Proton Center treats the following prostate cancers and genitourinary cancers with proton therapy.

Localized prostate cancer (very low, low, intermediate and high risk)

Localized prostate cancer, which includes stage 1, stage 2, and stage 3 cancer, that has not grown into nearby tissues or more distant body parts. There are three types:

  • Very-low-risk and low-risk prostate cancer, each of which are unlikely to grow or spread for a long time, if at all.
  • Intermediate-risk prostate cancer, which may grow or spread in a few years.
  • High-risk prostate, which has the highest likelihood of spreading and, even after treatment, recurring.
Lymph node-positive prostate cancer

Prostate cancer will sometimes grow quickly and spread to lymph nodes, pea-sized pieces of tissue that filter a waste product called lymph.  When this happens, a larger area needs to be targeted for treatment that includes the prostate gland and the lymph nodes.  Proton therapy is particularly beneficial when treating large areas in the pelvis.

Postoperative prostate cancer

Data suggest that men who have undergone prostatectomy for prostate cancer may benefit from follow-up treatment with proton therapy, depending on several factors:

  • Gleason score
  • Seminal vesicle and lymph nodes involvement
  • PSA levels
Bladder cancer

Bladder cancers have a high correlation to prostate cancer. The types are named for the cells they affect, usually in the bladder wall.

  • Urothelial carcinoma (or “transitional cell carcinoma”) is by far most common, causing uncontrolled tumor growth in the innermost cells lining the bladder.
  • Squamous cell carcinoma is the result of bladder inflammation or irritation occurring over many months or years.
  • Adenocarcinoma forms in cells that make up glands.
Kidney cancer

Kidney cancer is an abnormal growth of cells in kidney tissue that eventually forms a tumor. Cells can break off from the tumor and spread to other tissue and organs. The most common kidney cancer is renal cell carcinoma.

 

Kidney cancer patients are at increased risk of prostate cancer.

Recurrent prostate or other genitourinary cancer

Among men treated for prostate cancer, up to 30 percent see their cancer return. Fewer than half of them can be cured by traditional treatment.

 

Proton therapy can treat these “recurrent” tumors more safely than other methods, giving patients a better chance for a cure.

Pencil Beam Scanning: Highly advanced proton therapy for prostate cancer

At the New York Proton Center, patients with prostate and other genitourinary cancers receive Pencil Beam Scanning. It’s the most sophisticated and precise type of proton therapy.

 

Pencil Beam Scanning allows clinicians to create a highly customized treatment field based on the unique shape, size and location of the prostate cancer tumor—similar to traditional proton therapy, only with even greater precision.

 

As the name implies, Pencil Beam Scanning uses an extremely narrow beam—just a few millimeters wide—to “dot” protons onto the cancer. The process is repeated, layer by layer, like paint applied by the tip of an incredibly fine brush. The treatment is ultra-precise, capable of closely regulating the radiation dose according to the volume of the tumor.

 

A tailored approach to treating prostate cancer with proton therapy

Most proton centers treat prostate cancer with volumetric beams that deliver a fixed quantity of energy to the entire tumor and surrounding normal tissues. But the Pencil Beam Scanning technology available at the New York Proton Center uses “intensity-modulated proton therapy,” or IMPT.

 

IMTP is widely considered the most advanced form of proton therapy for prostate cancer. It delivers different radiation doses to different parts of the tumor based on its exact location, maximizing the chance of a cure while better protecting surrounding healthy tissue from radiation.

How can we help?

Want to find out if proton therapy might be a good fit for you or your patient? Call us at 833-NYPROTON (833-697-7686) or fill out the appropriate form below.