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5-Fraction SBRT Proton Therapy: A Game-Changer in Prostate Cancer Treatment

Men’s Health Month in June shed additional light on prostate cancer – a significant health concern that affects millions of men worldwide. Thanks to advancements in medical technology, evolved treatment options offer improved outcomes and reduced side effects. Among these groundbreaking therapies, 5-fraction SBRT (stereotactic body radiation therapy) proton therapy has emerged as a highly effective modality – and a form of treatment we offer here at NYPC.


Prostate cancer is a prevalent and potentially life-threatening disease, with one in eight men expected to receive this diagnosis in their lifetime. Traditional treatment approaches for prostate cancer, such as surgery or conventional radiation therapy, often come with significant side effects and prolonged treatment durations. However, advancements in radiation therapy techniques, such as 5-fraction SBRT with proton therapy, are improving the landscape of prostate cancer treatment and improving both patient convenience and clinical outcomes.


Five-fraction SBRT is an innovative and precise radiation therapy approach that differentiates itself from standard radiotherapy treatments. It utilizes highly focused radiation beams to deliver a higher dose per treatment session over just five days, with sessions occurring every other day. This accelerated treatment schedule significantly reduces the overall treatment duration compared to standard five-plus-week courses of radiation therapy. The convenience of the accelerated treatment schedule enables patients to complete therapy more efficiently, reducing their time commitment without compromising outcomes.


One of the key advantages of 5-fraction SBRT treatment for prostate cancer is its exceptional precision. By utilizing advanced imaging and targeting techniques, such as pencil beam scanning technology, protons are precisely directed to the tumor site while sparing surrounding healthy tissues. This level of accuracy is important in prostate cancer treatment due to the gland’s proximity to vital organs like the bladder, bowel, and rectum.


Existing data and clinical trials have shown promising results regarding the efficacy and tolerability of 5-fraction SBRT proton therapy for prostate cancer. Research indicates that the treatment’s side effect profile is mild and comparable to that of longer treatment regimens, minimizing disruptions to patients’ daily lives. Furthermore, the effectiveness of 5-fraction SBRT is on par with the standard prolonged course of proton therapy, ensuring patients receive optimal care while being able to receive a reduced treatment duration.


The adoption of 5-fraction proton SBRT treatment represents a significant milestone in the field of prostate cancer therapy. Many cancer centers offer photon-based SBRT such as CyberKnife, and many proton centers offer a protracted course of treatment for prostate cancer, but only a handful of centers in the world offer both the convenience of a 5-fraction course with the ultra-precision of proton therapy. As technology continues to advance, NYPC and other pioneering institutions are committed to ongoing research and clinical trials to further refine and expand the application of this cutting-edge treatment. At NYPC, our proton therapy research program encompasses 25 clinical trials, including two specifically focused on prostate cancer, one of them to further demonstrate the effectiveness for this 5-fraction SBRT treatment.


Men’s Health Month provided an opportunity to spotlight the importance of proactive healthcare screenings and cutting-edge therapies like 5-fraction SBRT for prostate cancer. By leveraging these advancements, we can empower men with better treatment options and improve outcomes in the battle against prostate cancer, ultimately paving the way for a healthier future for men worldwide.

How can we help?

Want to find out if proton therapy might be a good fit for you or your patient? Call us at 833-NYPROTON (833-697-7686) or fill out the appropriate form below.